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Page 26 of 26 · 501 total

Exploiting mitochondrial targeting signal(s), TPP and bis‐TPP, for eradicating cancer stem cells (CSCs)

06-01-2018

TPP-related compounds may provide a novel chemical strategy for effectively targeting bulk cancer cells and CSCs, while minimizing off-target side-effects in normal cells. Several independent lines of evidence support the idea that increased mitochondrial biogenesis or higher levels of mitochondrial protein…

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