Figure 6 — High glucose enhances fibrosis in human annulus fibrosus cells by activating mTOR, PKCδ, and NF-κB signaling pathways

Research Paper|Volume 16, Issue 11|pp. 9460–9469

High glucose enhances fibrosis in human annulus fibrosus cells by activating mTOR, PKCδ, and NF-κB signaling pathways

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Figure 6.Schematic illustration showing signaling pathways involved in HG-facilitated fibrosis in IVDD. HG enhances fibrotic protein expression in HAFCs through mTOR, PKCδ and NF-κB pathways during IVDD progression.