Figure 7 — HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2

Research Paper|Volume 15, Issue 23|pp. 13888–13900

HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2

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Figure 7.HACE1 promoted NRF2 activity levels by its Ubiquitination in model of heart failure. NRF2 protein expression (A–C), HACE1 and NRF2 expression (Microscopic display, (D), ACE1 protein connected with NRF2 protein (IP, E), NRF2 Ubiquitination (F). ##p<0.01 compared with control group or si-nc group.