Figure 4 — Regulatory mechanisms of miR-212-3p on the secretion of inflammatory factors in monocyte-macrophages and the directed differentiation into osteoclasts in ankylosing spondylitis

Research Paper|Volume 15, Issue 22|pp. 13411–13421

Regulatory mechanisms of miR-212-3p on the secretion of inflammatory factors in monocyte-macrophages and the directed differentiation into osteoclasts in ankylosing spondylitis

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Figure 4.(A) Protein expression of p-ERK1/2, t-ERK1/2, MMP-1, MMP-3, IL-1β and TNF-α in monocyte-macrophage cells was detected by Western blot (ERK: extracellular signal-regulated kinase; MMP: matrix metalloproteinase; IL-1β: interleukin-1β; TNF-α: tumor necrosis factor α). (B) Statistical histogram of relative protein expression.