Figure 2 — SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

Research Paper|Volume 14, Issue 24|pp. 10081–10092

SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

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Figure 2.The roles of SALL4 on the proliferation of hepatoma tested by CCK8 assay. SALL4 mimic increased the OD value in both HepG2 (A) and SMMC-7721 cells (B); and SALL4 inhibited the OD value in both HepG2 (A) and SMMC-7721 cells (B) n = 3/group, t test between two groups, and by one-way analysis of variance among groups. ^*p < 0.05, ^**p < 0.01 mimic vs. mimic NC group, ^#p < 0.05, ^##p < 0.01 inhibitor vs. inhibitor NC group.