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Figure 5
Figure 5.miR-497 inhibitor increased the expression of the viability, migration, and invasion biomarker genes. qRT-PCR assay analysis of Ki67, CD147, MMP-2 expression level in CSCs and non-CSCs isolated from populations of AsPC-1 and BxPC-3 cells. ***P< 0.001, compared to the NC group; ###P< 0.001, compared to the NC+gemcitabine group. Data are shown as mean ± SEM. All experiments were repeated at least three independent experiments.
Figure 5 — microRNA-497 prevents pancreatic cancer stem cell gemcitabine resistance, migration, and invasion by directly targeting nuclear factor kappa B 1 | Aging