Figure 1 — Coupling of serum CK20 and hyper-methylated CLIP4 as promising biomarker for colorectal cancer diagnosis: from bioinformatics screening to clinical validation

Research Paper|Volume 13, Issue 24|pp. 26161–26179

Coupling of serum CK20 and hyper-methylated CLIP4 as promising biomarker for colorectal cancer diagnosis: from bioinformatics screening to clinical validation

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Figure 1.The serum levels of CEA, CK18, CK20, CK8, MUC13 and EPCAM in CRC, CA patients and healthy controls. (A) Screening specific genes that encode secretory proteins in CRC by bioinformatics. (B) Testing the expression of candidate serum biomarker genes by Q-PCR in 8 cell lines. (C) Detection of the serum levels of CEA, CK18, CK20, CK8, MUC13 and EPCAM in CRC, CA patients and healthy controls by ELISA.