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Research Paper|Volume 13, Issue 20|pp. 23652–23671
Up-regulation of SIRT1 induced by 17beta-estradiol promotes autophagy and inhibits apoptosis in osteoblasts
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Figure 10
Figure 10.The diagram describes the underlying mechanism that the up-regulation of SIRT1 induced by 17β-E2 could promote autophagy via the AMPK-mTOR pathway and inhibit apoptosis by the FOXO3a activation.