Figure 4.MiR-539-5p targeted CDK6. (A, B) Relative expression of CDK6 after transfection with miR-539-5p inhibitors or mimics. (C) Predicted binding site in CDK6 with miR-539-5p through TargetScan. (D, E) Luciferase reporter assay and RIP assay were conducted to validate the interaction between miR-539-5p and CDK6. *P<0.05.
