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Online ISSN: 1945-4589

Research Paper|Volume 12, Issue 18|pp. 18343–18362

Modeling mtDNA hypermethylation vicious circle mediating Aβ-induced endothelial damage memory in HCMEC/D3 cell

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−100%+

Figure 3.(A) The change of AKG, MMP, and cell vitality in decitabine treated hCMEC/D3 cell. The control group data is normalized to 100%. (B) The change of mtDNA methylation, MMP, and cell vitality in AKG treated hCMEC/D3 cell. The control group data is normalized to 100%. ** p<0.01 * p<0.05.