Figure 6 — Hydrostatic pressure induces osteogenic differentiation of adipose-derived mesenchymal stem cells through increasing lncRNA-PAGBC

Research Paper|Volume 12, Issue 13|pp. 13477–13487

Hydrostatic pressure induces osteogenic differentiation of adipose-derived mesenchymal stem cells through increasing lncRNA-PAGBC

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Figure 6.Schematic of the model. HP induces upregulation of PAGBC, which binds to miR-133b to prevent its suppression on translation of RUNX2, resulting in enhanced RUNX2-mediated osteogenic differentiation of AMSCs.