Figure 4.NBP attenuated inflammation and brain edema in intracerebral hemorrhage. NBP treatment substantially inhibit the inflammation, reduced ICH-induced brain edema, and then protected the BBB from disruption. BBB: blood-brain barrier; CNS: central nervous system; MMP-9: matrix metalloproteinase-9; NBP: butylphthalide; ROS:reactive oxygen species; TNF-α: tumor necrosis factor-alpha.
