Figure 2 — Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats

Research Paper|Volume 12, Issue 13|pp. 12799–12811

Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats

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Figure 2.Tomatidine-target genes associated with the top two KEGG pathways. (A) The tomatidine-target genes that are part of the MAPK signaling pathway, including MAPK1 and MAPK3 are associated with proliferation, differentiation, cell survival or anti-apoptotic, and inflammation. (B) Tomatidine-target genes that are part of the Neurotrophin signaling pathway, including MAPK1 and MAPK3 are associated with cellular differentiation, cell survival, and retrograde transport.