Figure 3.STK40 knockout inhibits HF keratinocyte differentiation and hair growth, but facilitated the apoptosis. (A) Hair loss conditions of STK40-/- mice at 30 days postnatal. (B) Delayed hair growth in STK40-/- mice. (C) HF neogenesis in STK40-/- mice and WT mice as determined by ALP staining. (D) Expression of the corresponding proliferation, differentiation, and apoptosis markers in the skin samples of STK40-/- and WT mice as detected by immunofluorescence assay (400 ×). * p < 0.05 vs. WT mice; Measurement data were expressed as mean ± standard deviation. Unpaired t test was adopted to analyze the differences between two experimental groups. n = 15.
