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Online ISSN: 1945-4589
Research Paper
|
Volume 12, Issue 3
|
pp. 2440–2452
HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB
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Figure 8
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Figure 8.
Schematic diagram shows potential mechanism of action of HO-1.
HO-1 promotes autophagy by increasing the formation of the Beclin-1/PI3KC3 complex. HO-1 induced autophagy protects against apoptosis of human NPCs by inhibiting NF-κB.