Figure 3 — Grape seed proanthocyanidins ameliorate neuronal oxidative damage by inhibiting GSK-3β-dependent mitochondrial permeability transition pore opening in an experimental model of sporadic Alzheimer’s disease

Research Paper|Volume 11, Issue 12|pp. 4107–4124

Grape seed proanthocyanidins ameliorate neuronal oxidative damage by inhibiting GSK-3β-dependent mitochondrial permeability transition pore opening in an experimental model of sporadic Alzheimer’s disease

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Figure 3.GSPs inhibited STZ-induced Aβ accumulation and phosphorylation of tau in vivo. (A and B) Representative immunoblot bands for APP, Aβ, p-tau and tau in the cerebral cortex and hippocampus, respectively. (C–F) Quantification analysis of immunoblot bands. Protein expression levels were normalized to β-actin. ^*P < 0.05 vs Sham; ^#P < 0.05 vs STZ, n=4-6.