Figure 3.Therapeutic targeting of e-CSCs. Experimentally, both an OXPHOS inhibitor (Diphenyleneiodonium; DPI) and a CDK4/6 (Ribociclib) inhibitor were effective in abrogating the 3D-propagation of e-CSCs.
Figure 3 — Hallmarks of the cancer cell of origin: Comparisons with “energetic” cancer stem cells (e-CSCs) | Aging
