Figure 1 — Telomerase and estrogen-sensing activities are essential for continued mammary growth in vivo but dispensable for “reprogramming” neural stem cells

Research Paper|Volume 8, Issue 7|pp. 1353–1362

Telomerase and estrogen-sensing activities are essential for continued mammary growth in vivo but dispensable for “reprogramming” neural stem cells

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Figure 1.Shortened telomeres lead to enhanced mammary gland senescence upon serial transplantationWhole mounted glands from TER^+/+ (A-C), TER^+/− (D-F), and TER^−/− (g1 G-I, g5 J-L) transplanted tissues from early transplant generations 1 and 2 (A,D,G,J), middle transplant generation 3 (B, E, H, K), and late transplant generations 4 and 5 (C, F, I, L). Scale bars: 2mm.