Figure 1 — Metformin and the ATM DNA damage response (DDR): Accelerating the onset of stress-induced senescence to boost protection against cancer

Research Perspective|Volume 3, Issue 11|pp. 1063–1077

Metformin and the ATM DNA damage response (DDR): Accelerating the onset of stress-induced senescence to boost protection against cancer

Back to articleFigure 1(1 of 3)

100%

Figure 1.Chronic exposure to metformin suppresses the proliferative activity of human [A431] cancer cells (A) to enter a form of permanent cell-cycle arrest accompanied by the induction of “self-digesting” autophagy (B).