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Figure 3.Cisplatin induces the p-ΔNp63α and LKB1 protein levels in SCC cellsWild type ΔNp63α cells and ΔNp63α-S385G cells were exposed to control media and 10μg/ml cisplatin for 24h. Protein levels were tested with indicated antibodies. Cytoplasmic (cyto) protein levels were tested with the anti-β-actin antibody. (A) No lactacystin treatment. (B) With lactacystin treatment.
Figure 3 — Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells | Aging