Figure 10.Outline of pro- and anti-aging processes that are controlled by the TOR and/or cAMP/PKA signaling pathways and are modulated by LCA or rapamycin (RAP) in chronologically aging yeast.The
currently accepted (A) and updated, based on this study (B),
outlines of pro- and anti-aging processes are shown. Activation
arrows and inhibition bars denote pro-aging processes (displayed in green
color), anti-aging processes (displayed in red color) or processes whose
role in longevity regulation was unknown (displayed in black color). Doted
lines denote hypothetical, until this study, processes. See text for
details.
