Figure 5.Effects of COX-1 deficiency on PG production 24 h after Aβ 1-42 administration. Aβ1-42-injected
WT mice show significantly more PGE2
(A), PGF2α (B), and TXB2 levels (C)
than COX-1-/- mice. Mean ± SEM (n = 3-4 per
group); *P < 0.05, **P < 0.01
compared with the Aβ42-1-injected WT mice; #P
< 0.05, ##P < 0.01 compared with the Aβ1-42-injected
WT mice.