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COVID-19Review|Volume 12, Issue 18|pp 18754—18764

Neurological manifestations in COVID-19 and its possible mechanism

Xiaojia Tang1,2, Yuhan Luo1,2, Yuxia Song1,2, Hongyang Fan2, Sisi Dong3, Peipei Liu2, Yingzhu Chen2
  • 1Department of Neurology, Dalian Medical University, Dalian 116000, Liaoning, China
  • 2Department of Neurology, Clinical Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China
  • 3The Second Xiangya Hospital, Central South University, Changsha 410000, Hunan Province, China
* Equal contribution
Received: March 22, 2020Accepted: July 7, 2020Published: September 27, 2020
https://doi.org/10.18632/aging.103732

Copyright: © 2020 Tang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

In December 2019, the first cases of the acute respiratory illness now known as Corona Virus Disease 2019 (COVID-19) occurred in Wuhan, Hubei Province, China. The main clinical manifestations of COVID-19 are a fever, dry cough and general weakness, although in some patients, a headache, tight chest, diarrhea, etc. are the first clinical manifestations. Neurological practice is involved in all aspects of medicine, from primary care for patients with migraines to consultations with patients in the intensive care unit. Few disorders spare the nervous system, and newly emerging infections are no exception. As neurologists, we are concerned about the effects of SARS-CoV-2 infections on the nervous system. Multiple neuropathy, rhabdomyolysis, cerebrovascular disease, central nervous system infections and other common neurological diseases require attention during this outbreak.