Changbin Lei1,Department of Orthopaedic Surgery, The First Affiliated Hospital of Jinan University, Guangdong 510630, China2,Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA3Department of Orthopaedic Surgery, Affiliated Hospital of Xiangnan University, Hunan 423000, China, Debora Colangelo4Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33410, USA, Prashanti Patil2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA, Vivian Li2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA, Kevin Ngo2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA, Dong Wang2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA, Qing Dong2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA, Matthew J. Yousefzadeh5Department of Biochemistry, Molecular Biology and Biophysics, The Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN 55455, USA, Hongsheng Lin3Department of Orthopaedic Surgery, Affiliated Hospital of Xiangnan University, Hunan 423000, China, Joon Lee2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA, James Kang5Department of Biochemistry, Molecular Biology and Biophysics, The Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN 55455, USA, Gwendolyn Sowa2,Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA7Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA, Tony Wyss-Coray8Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA, Laura J. Niedernhofer5Department of Biochemistry, Molecular Biology and Biophysics, The Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN 55455, USA, Paul D. Robbins5Department of Biochemistry, Molecular Biology and Biophysics, The Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN 55455, USA, Derek M. Huffman9Departments of Molecular Pharmacology and Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Nam Vo2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA
- 1Department of Orthopaedic Surgery, The First Affiliated Hospital of Jinan University, Guangdong 510630, China
- 2Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh, E1641 Biomedical Science Tower, Pittsburgh, PA 15213, USA
- 3Department of Orthopaedic Surgery, Affiliated Hospital of Xiangnan University, Hunan 423000, China
- 4Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33410, USA
- 5Department of Biochemistry, Molecular Biology and Biophysics, The Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN 55455, USA
- 6Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
- 7Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA
- 8Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
- 9Departments of Molecular Pharmacology and Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA